Cannabidiol (CBD) is a naturally occurringcannabinoid constituent of cannabis. It was discovered in 1940 and initially thought not to be pharmaceutically active. 大麻二酚（CBD）是大麻中天然存在的大麻素成分。 它於1940年被發現，最初被認為不具有藥物活性。 It is one of at least 113 cannabinoids identified in hempplants, accounting for up to 40% of the plant's extract.[8] As of 2018 in the United States, Food and Drug Administration approval of cannabidiol as a prescription drug called Epidiolex for medical uses has been limited to two rare forms of childhood epilepsy. 它是大麻植物中鑑定出的至少113種大麻素之一，佔該植物提取物的40％。[8] 截至2018年，美國食品和藥物管理局批准大麻酚作為處方藥稱為Epidiolex用於醫療用途，僅限於兩種罕見的兒童癲癇形式。
Cannabidiol can be taken into the body in multiple different ways, including by inhalationof cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as an oil containing only CBD as the active ingredient (no added THC or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.
大麻二酚可以多種不同的方式進入體內，包括吸入大麻煙或蒸氣，氣溶膠噴入面頰和口腔。 它可以作為僅含有CBD作為活性成分（不添加THC或萜烯）的油，全植物CBD主要的大麻提取油，膠囊，乾燥的大麻或作為處方液溶液提供。
大麻二酚（CBD）是大麻的主要非精神科成分，具有多種藥理作用，包括抗焦慮、抗精神病、止吐和抗炎特性。該綜述根據Web of Science，Scielo和Medline檢索的報告描述了廣泛濃度CBD給藥的多項研究表明，CBD在非轉化細胞中無毒性，不會誘發食物攝入變化，不會誘發全身僵硬症，不會影響生理參數（心率、血壓和體溫），不會影響胃腸道的轉運和不會改變精神運動或心理功能。
It’s hard to say the precise moment when CBD, the voguish cannabis derivative, went from being a fidget spinner alternative for stoners to a mainstream panacea.
drugsSlang for somebody who smokes cannabis, often. Most people would talk them down as if they are better, though they often consume poisons such as alcohol and caffeine. Stoners are generally a friendly minority, peaceful, and harmless. The arrogant people bitching about them smoking marijuana, they are usually bigger problems then the people they denounce.
Either way, it would be hard to script a more of-the-moment salve for a nation on edge. With its proponents claiming that CBD treats ailments as diverse as inflammation, pain, acne, anxiety, insomnia, depression, post-traumatic stress and even cancer, it’s easy to wonder if this all natural, non-psychotropic and widely available cousin of marijuana represents a cure for the 21st century itself.
The ice caps are melting, the Dow teeters, and a divided country seems headed for divorce court. Is it any wonder, then, that everyone seems to be reaching for the tincture?
“Right now, CBD is the chemical equivalent to Bitcoin in 2016,” said Jason DeLand, a New York advertising executive and a board member of Dosist, a cannabis company in Santa Monica, Calif., that makes disposable vape pens with CBD. “It’s hot, everywhere and yet almost nobody understands it.”
Cannabis for Non-Stoners
With CBD popping up in nearly everything — bath bombs, ice cream, dog treats — it is hard to understate the speed at which CBD has moved from the Burning Man margins to the cultural center.
A year ago, it was easy to be blissfully unaware of CBD. Now, to measure the hype, it’s as if everyone suddenly discovered yoga. Or penicillin. Or maybe oxygen.
Even so, you ask, what is CBD? Plenty of people still have no idea. CBD is short for cannabidiol, an abundant chemical in the cannabis plant. Unlike its more famous cannabinoid cousin, THC (tetrahydrocannabinol), CBD does not make you stoned.
Which is not to say that you feel utterly normal when you take it.
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CBD drops by a New York start-up called Plant People. The product purports to relieve stress, reduce pain and improve cognition. CreditJules Davies
Users speak of a “body” high, as opposed to a mind-altering one. “Physically, it’s like taking a warm bath, melting the tension away,” said Gabe Kennedy, 27, a founder of Plant People, a start-up in New York that sells CBD capsules and oils. “It is balancing; a leveling, smoothing sensation in the body mostly, and an evenness of attention in the mind.”
Comparing it to the feeling after an intense meditation or yoga session, Mr. Kennedy added that the CBD glow has “synergistic downstream effects” in terms of social connections. “Around others, I find myself more present and attentive, more creative and open.”
Moreover, you are unlikely to find yourself microwaving frozen burritos at midnight after taking CBD, unlike with pot.
Such quasi-religious talk is common among CBD’s disciples.
“I’m a 30 y.o. male who has not experienced a single anxiety free day in my adult life,” wrote one user on a CBD forum on Reddit earlier this month. “About 3 weeks ago I started taking CBD-oil 10 percent and I can’t even describe how amazing I feel. For the first time in 15+ years I feel happy and look forward to living a long life.”
Such testimonials make CBD seem like a perfect cure for our times. Every cultural era, after all, has its defining psychological malady. This also means that every era has its signature drug.
The jittery postwar era, with its backyard bomb shelters and suburban fears about keeping up with the Joneses, gave rise to a boom in sedatives, as seen in the era’s pop songs (“Mother’s Little Helper,” by the Rolling Stones) and best sellers (“Valley of the Dolls,” by Jacqueline Susann).
The recessionary 1990s gave rise to Generation X angst, Kurt Cobain dirges and a cultural obsession with newfangled antidepressants (see Elizabeth Wurtzel’s “Prozac Nation: Young and Depressed in America”).
The defining sociological condition today, especially among millennials, is arguably anxiety: anxiety about our political dysfunction, anxiety about terrorism, anxiety about climate change, anxiety about student loan debt, even anxiety about artificial intelligence taking away all the good jobs.
The anxiety feels even more acute since the wired generation feels continuously bombarded by new reasons to freak out, thanks to their smart devices.
“You are inundated with terrible news, and you have no choice to opt in or out,” said Verena von Pfetten, 35, the former digital director for Lucky magazine who is a founder of Gossamer, a high-style magazine targeted to cannabis-loving tastemakers. “You open your computer, check your phone, there are news alerts.”
What a convenient time for Mother Nature to bestow a perma-chillax cure that seems to tie together so many cultural threads at once: our obsession with self-care and wellness, the mainstreaming of alternative therapies and the relentless march of legalized marijuana.
“That seems like a gift in these times,” Ms. von Pfetten said.
‘The New Avocado Toast’
The tsunami of CBD-infused products has hit so suddenly, and with such force, that marketers have strained to find a fitting analogy. Chris Burggraeve, a former Coca-Cola and Ab InBev executive, called it the “new avocado toast,” in an interview with Business Insider.
Then again, avocado toast seems so five years ago.
Fad chasers looking for the next-next big thing may want to check out the CBD-infused ricotta-and-honey toast at Chillhouse, the Instagram-ready coffee shop, nail salon and massage studio on the Lower East Side of Manhattan. And then retreat to Inscape NYC, a meditation and relaxation studio in Chelsea, to unwind with a stress-busting CBD Saturday session.
It would be false to suggest CBD is nothing more than an obsession for reiki-adjacent bicoastal millennials. According to the AARP website, CBD has become a popular treatment for pain and arthritis among baby boomers, some of whom may have been out of the cannabis game since they rolled their last doobie at a Foghat concert in 1975.
Even so, CBD seems to have found its natural target audience among the vegan-curious creative professionals who cluster in trendy hotels like the James New York-Nomad hotel, which offers a room-service CBD tasting menu featuring CBD-infused meatballs and sriracha-mayo House Tots. Or the Standard hotel outposts in Miami and New York, which sell $50 blood orange-flavored gumdrops by the upscale CBD brand Lord Jones in its minibars.
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Such sumptuously packaged, premium-priced CBD products appeal to trend-conscious consumers in part because they promise a degree of indulgence — without the indulgence.
Despite its cannabis origins, CBD is not marketed as a recreational drug, but almost as its opposite: as a corrective to the ill effects of alcohol and even marijuana itself, which makes it catnip for hard-charging professionals who need to be fresh for a 7 a.m. breakfast meeting.
A detox drink under development called Sober Up, for example, will contain CBD and is supposed to support liver health and help prevent hangovers.
Fewer hangovers is also the sales pitch at Adriaen Block, a bar in the Astoria neighborhood of Queens that whips up CBD-infused negronis and old-fashioned cocktails. “You can maintain a conversation and know what you are saying,” said Zsolt Csonka, who own’s the bar and mixes drinks there. “After two or three drinks, you’ll be able to go to the gym the next day.When added to dishes like sesame shrimp toast atPopCultivate, a series of cannabis-centric pop-up dinners in Los Angeles, CBD (which is flavorless) can function as a social lubricant, just like a wine pairing, but without, according to proponents, the hangover.
“You become more engaged with your neighbors, talk more freely, and meet more people you dine with,” said Chris Yang, the molecular biologist turned chef behind the series.
But nowhere does the fervor for CBD seem greater than in health and beauty, where cannabidiol is often packaged with buzzy terms like “single origin,” “small batch” and “plant based.”
Among beauty products alone, CBD has already achieved cliché status, popping up in blemish creams, sleeping masks, shampoos, hair conditioners, eye serums, anti-acne lotions, mascaras, massage oils, soaps, lip balms, bath bombs, anti-wrinkle serums, muscle rubs and a Sephora aisle’s worth of moisturizers, face lotions and body creams. Even the bedroom is not safe from the CBD invasion, to judge by the spate of CBD sexual lubricants on shelves.
This earthy, artisanal aura plays well with devotees of, say, Goop, who are already conditioned, after years of aromatherapy, cryotherapy and homeopathy, to accept a natural wellness mantra over anything on offer by Big Pharma and the medical industrial complex.
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